منابع مشابه
Dendrites as separate compartment - local protein synthesis.
The article summarizes the most meaningful studies which have provided evidence that protein synthesis in neurons can occur not only in cell perikarya but also locally in dendrites. The presence of the complete machinery required to synthesize cytoplasmic and integral membrane proteins in dendrites, identification of binding proteins known to mediate mRNA trafficking in dendrites and the abilit...
متن کاملSnapShot: Local Protein Translation in Dendrites
Neuron Local synthesis Replenishment of distal synapses LTP Input specificity Synaptic protein turnover and plasticity Microtubule RER Spine apparatus Polysome RNP Kinesin Protein synthesis machinery mRNA transport Turnover and modification of the synaptic proteome The local transcriptome and the synaptic translation machinery Direct capture and synaptic tagging Synthesis (tag) Capture Stoichio...
متن کاملساختار کلاسهایی از حلقه های z- موضعی و c- موضعی the structure of some classes of z-local and c-local rings
فرض کنیمr یک حلقه تعویض پذیر ویکدار موضعی باشدو(j(r رایکال جیکوبسن r و(z(r مجموعه مقسوم علیه های صفر حلقه r باشد.گوییم r یک حلقه z- موضعی است هرگاه j(r)^2=. .همچنین برای یک حلقه تعویض پذیر r فرض کنیم c یک عنصر ناصفر از (z( r باشد با این خاصیت که cz( r)=0 گوییم حلقه موضعی r یک حلقه c - موضعی است هرگاه و{0 و z(r)^2={cو z(r)^3=0, نیز xz( r)=0 نتیجه دهد که x عضو {c,0 } است. در این پایان نامه ساخ...
Regulation and function of local protein synthesis in neuronal dendrites.
It has long been shown that protein synthesis can occur in neuronal dendrites, but its significance remained unclear until relatively recently. Studies suggest that local protein synthesis has crucial roles in synaptic plasticity, the change in neuronal communication efficiency that is probably a cellular basis of learning and memory. Induced by neuronal activity, local protein synthesis provid...
متن کاملRNA trafficking and local protein synthesis in dendrites: an overview.
It is now widely accepted that mRNAs localize to dendrites and that translation of these mRNAs is regulated in response to neuronal activity. Recent studies have begun to reveal the underpinnings of these processes and to underscore the importance of local protein synthesis to synaptic remodeling and plasticity. When Steward and Levy (1982) first reported their observation of polyribosomes at t...
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ژورنال
عنوان ژورنال: Topology and its Applications
سال: 1985
ISSN: 0166-8641
DOI: 10.1016/0166-8641(85)90034-3